Original Research

Left ventricular remodeling in patients with acute myocardial infarction under conservative and interventional treatment

L.M. Babii, N.P. Stroganova, Yu.O. Khomenko

National Scientific Center «M.D. Strazhesko Institute of Cardiology NAMS of Ukraine», Kyiv, Ukraine

The aim – to study peculiarities of left ventricular remodeling in early terms of acute myocardial infarction (AMI) depending on the treatment (conservative – drug treatment or interventional – stenting of the infarct-dependent coronary artery).

Materials and methods. The study included 81 patients with Q-AMI. Among them, 42 (51.9 %) pts (1st group) received standard drug treatment. Stenting of the infarct-dependent coronary artery was performed in 39 (48.1 %) pts (2nd group) in 4–12 hs after start of the symptoms. Hemodynamic parameters were studied by means of echocardiography.

Results. Independent of treatment, the typical changes of hemodynamics in early terms after AMI are early postinfarction left ventricular dilatation, left ventricular hypertrophy and functional changes. Maintenance of left ventricular systolic function is due not only by changes of end-systolic volume and left ventricular mass index, but also due to factors determining adaptive myocardial mechanisms (myocardial contractile function and possibility to involve myocardial reserve).

Conclusions. Course of the early left ventricular remodeling after Q-AMI doesn’t depend on the treatment tactics which corresponds to the literature data.

Кey words: acute myocardial infarction, treatment, myocardial remodeling.