Echocardiography in acute critical care in cardiology

N.D. Oryshchyn

References

1.Бучнєва О.В. Інструментальні методи дослідження при гострих аортальних синдромах: переваги та недоліки методів // Кардіологія та кардіохірургія: безперервний професійний розвиток.– 2019.– № 2 (2).– С. 44–52. doi:  10.30702/ccs.201905.02.0094452.
2.Іванів Ю.А., Лозинська Н.В., Орищин Н.Д., Іванів І.Ю. Допплерівські методи в ехокардіографічній діагностиці перикардитів // Здоров’я України.– 2013.– № 6.– С. 26–27.
3.Коваленко В.М., Ю.А. Іванів Ю.А., Долженко М.М. Кількісна ехокардіографічна оцінка порожнин серця Рекомендації робочої групи з функціональної діагностики Асоціації кардіологів України та Всеукраїнської громадської організації «Асоціація фахівців з ехокардіографії» акад. НАМН України // Новини медицини та фармації. Кардіологія.– 2011.– C. 359. 
4.Коваленко В.М., Несукай О.Г. та ін. Діагностика та лікування хвороб перикарда. Рекомендації робочої групи з хвороб міокарда, перикарда, ендокарда та клапанів серця Асоціації кардіологів України // Укр. кардіол. журн.– 2016.– № 2.– С. 86–95.
5.Орищин Н.Д., Іванів Ю.А. Ехокардіографічна діагностика гострого аортального синдрому // Серцево-судинна хірургія. Щорічник наукових праць асоціації серцево-судинних хірургів України.– 2008.– Вип. 16.– C. 304–306.
6.Орищин Н.Д. Ехокардіографічна діагностика механічних ускладнень інфаркту міокарда // Кардіохірургія та інтервенційна кардіологія.– 2016.– № 1.– С. 26–35.
7.Dresden S., Mitchell P., Rahimi L. et al. Right ventricular dilatation on bedside echocardiography performed by emergency physicians aids in the diagnosis of pulmonary embolism // Ann. Emerg. Med.– 2014.– Vol. 63 (1).– P. 16–24.
8.Evangelista A., Maldonado G., Gruosso D. et al. The current role of echocardiography in acute aortic syndrome // Echo Research and Practice.– 2019.– Vol. 6 (2).– P. R53–R63. 
9.Evangelista A., Flachskampf F.A., Erbel R. et al. Echocardiography in aortic diseases: EAE recommendations for clinical practice // Eur. J. Echocardiogr.– 2010.– Vol. 11.– P. 645–658.
10. Galderisi M., Cosyns B., Edvardsen Tr. et al. Standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations: an expert consensus document of the European Association of Cardiovascular Imaging // Eur. Heart J. Cardiovasc. Imaging,– Vol. 18 (12).– P. 1301–1310. doi: 10.1093/ehjci/jex244.
11.Galie N., Humbert M, Vachier J. et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension // Eur. Heart J.– 2016.– Vol. 37 (1).– P. 67–119. doi: 10.1093/eurheartj/ehv317.
12.Ibanez B., James S., Agewall S. et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) // Eur. Heart J.– 2017.– Vol. 39 (2).– P. 119–177. doi: 10.1093/eurheartj/ehx393. 
13.Klein T., Ramani G. Assessment and management of cardiogenic shock in the emergency department. // Cardiol. Clin.– 2012.– Vol. 30.– P. 651–664.
14.Konstantinides S.V., Meyer G., Becattini C. et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC) // Eur. Heart J.– 2020.– Vol.  41 (4).– P. 543–603.  doi: 10.1093/eurheartj/ehz405.
15.Lancellotti P., Tribouilloy C., Hagendorff A. et al. Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging // Eur. Heart J.– Cardiovascular Imaging.– 2013.– Vol. 14.– P. 611–644.
16.Lancellotti P., Price S., Edvardsen T. et al. The use of echocardiography in acute cardiovascular care: Recommendations of the European Association of Cardiovascular Imaging and the Acute Cardiovascular Care Association // Eur. Heart J. Acute Cardiovasc. Care.– 2015.– Vol. 4 (1).– P. 3–5.
17.Lancellotti P., Pibarot P., Chambers J. et al Recommendations for the imaging assessment of prosthetic heart valves: a report from the European Association of Cardiovascular Imaging endorsed by the Chinese Society of Echocardiography, the Inter-American Society of Echocardiography, and the Brazilian Department of Cardiovascular Imaging // Eur. Heart J. Cardiovasc. Imaging.– 2016.– Vol. 17 (6).– P. 589–590. doi: 10.1093/ehjci/jew025. 
18.Neskovic A.N., Skinner H., Price S. et al. Focus cardiac ultrasound core curriculum and core syllabus of the European Association of Cardiovascular Imaging // Eur. Heart J. Cardiovasc. Imaging.– 2018.– Vol. 19 (5).– P. 475–481. doi: 10.1093/ehjci/jey006.
19.Nienaber C.A., Eagle K.A. Aortic Dissection: New Frontiers in Diagnosis and Management Part I: From Etiology to Diagnostic Strategies // Circulation.– 2003.– Vol. 108.– P. 628.
20.Zaidi A., Knight D.S., Augustine D.X. et al. Echocardiographic assessment of the right heart in adults: a practical guideline from the British Society of Echocardiography // Echo Res. Pract.– 2020.– Vol. 7 (1).– P. G19–G41. doi:10.1530/ERP-19-0051.
21.Zoghbi W., Chambers J., Dumesnil J. et al. Recommendations for evaluation of prosthetic valves with echocardiography and Doppler ultrasound // J. Am. Soc. Echocardiogr.– 2009.– Vol. 22.– P. 975–1014. 
22.Zoghbi W.A., Adams D., Bonow R.O. et al. Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular Magnetic Resonance // J. Am. Soc. Echocardiogr.– 2017.– Vol. 30 (4).– P. 303–371. doi: 10.1016/j.echo.2017.01.007. 

Valve dysfunction in patients with cardiac myxomas: mechanism of damage and methods of correction

R.M. Vitovskyi, V.V. Isaienko, D.M. Dyadyun, I.V. Martyshchenko, O.A. Pishchurin, O.V. Kupchinsky

References

1. Кнышов Г.В., Витовский Р.М., Захарова В.П. Опухоли сердца, проблемы диагностики и хирургического лечения.– K., 2005.– 24 c.
2. Константинов Б.А., Нечаенко МА, Винницкий Л.И. и др. Клинико-диагностические и прогностические аспекты миксомного синдрома // Современные инвазивные и неинвазивные методы диагностики.– М.: АИР-АРТ.– 2000.– С. 18–25.
3. Мирончик Е.В., Пырочкин В.М. Опухоли сердца // Журн. Гродненского государственного медицинского университета.– 2017.– № 1.– С. 87–93.
4. Шонбин А.Н., Мизинцова М.А., Миролюбова О.А., Антонов А.Б. Опухоли сердца: анализ хирургического лечения // Кардиология и сердечно-сосудистая хирургия.– 2016.– 9(4).– P. 39–42.
5. Akita M., Ando H., Iida Y. Papillary Fibroelastoma in the left ventricle resected under the guidance of a gastrointestinal fiberscope // Ann. Thor. Surgery.– 2009.– Vol. 87.– P. 928–930. doi: 10.1016/j.athoracsur.2008.07.044
6. Cianciulli T.F., Cozzarin A., Soumoulou J.B. et al. Twenty years of clinical experience with cardiac myxomas: diagnosis, treatment, and follow up // J. Cardiovasc. Imaging.– 2019.– Vol. 27 (1).– P.  37–47. doi:10.4250/jcvi.2019.27.e7.
7. Ciss A., Diarra O., N’diaye A. et al. Right ventricle myxoma obstructing partially right ventricular outflow tract // Internet J. Thoracic Cardiovasc. Surgery.– 2009.– Vol. 13 (2).
8. Grubb K.J., Jevremovic V., Chedrawy E.G. Mitral valve myxoma presenting with transient ischemic attack: a case report and review of the literature // J. Med. Case Rep.– 2018.– Vol. 12.– P. 363. doi:10.1186/s13256-018-1920-8.
9. Keeling I.M., Obervalder P. Cardiac myxomas: 20 years of experience in 49 patients // Eur. J. Cardiothorac. Surg.– 2002.– Vol. 22.– P. 971–977.
10. Kim D.S. A comprehensive perspective of clinical and echocardiographic features in the differential diagnosis of cardiac myxomas and myxoma-like masses // Korean Circ. J.– 2020.– Vol. 50 (9).– P.  833–835. doi: 10.4070/kcj.2020.0309.
11. Moyssakis I., Anastasiadis G. Second recurrence of cardiac myxoma in a young patient. A case report // Int. J. Cardiol.– 2005.– Vol. 101.– P.  501–502. doi: 10.1016/j.ijcard.2004.02.019.
12. Puntila J., Hakala T., Salminen J., Pihkala J. Positive genetic test led to an early diagnosis of myxoma in a 4-year-old boy // Inter. CardioVasc. Thorac. Surg.– 2006.– Vol. 5.– P. 662–663. doi: 10.1510/icvts.2006.134817.
13. Stern R. Cardiac myxomas // New Engl. J. Med.– 1996.– Vol. 334 (21).– P. 1408–1409.
14. Tyebally S., Chen B.D., Bhattacharyya S. et al. Cardiac Tumors: JACC Cardio-Oncology State-of-the-Art Revie // JACC: CardioOncology.–  2020.– Vol. 2, Issue 2.– P. 293–311.
15. Yoon S.J., Park S.C., You Y.P. et al. Multicentric biatrial myxoma in a young female patient: case report // Korean J. Intern. – 2000. – Vol. 15, N 3. – P. 236–239.

Clinical case of heart transplantation in the conditions of «the recipient-to-donor» transportation

B.M. Todurov, O.O. Samchuk, G.I. Kovtun, A.O. Shpachuk, M.V. Goncharenko, I.M. Kuzmich, O.M. Druzhina, O.A. Loskutov, O.I. Kvasha, S.M. Sudakevich, A.Yu. Melnik, Yu.I. Golik, R.V. Domashich, I.Z. Humenny

References

1. Dorent R., Gandjbakhch E., Goéminne C. et al. Assessment of potential heart donors: A statement from the French heart transplant community // Arch. Cardiovasc. Dis.– 2018.– Vol. 111 (2).– P. 126–139. doi: 10.1016/j.acvd.2017.12.001.
2. Kim I.C., Youn J.C., Kobashigawa J.A. The past, present and future of heart transplantation // Korean Crcul. J.– 2018.– Vol. 48 (7).– P. 565–590. doi: 10.4070/kcj.2018.0189.
3. Mehra M.R., Canter C.E., Hannan M.M. et al. International Society for Heart Lung Transplantation (ISHLT) Infectious Diseases, Pediatric and Heart Failure and Transplantation Councils. The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update // J. Heart Lung. Transplant.– 2016.– Vol. 35 (1).– P. 1–23. doi: 10.1016/j.healun.2015.10.023.
4. Nandkeolyar S., Kim H.B., Doctorian T. et al. A case report of heart transplant for ischaemic cardiomyopathy from lupus coronary vasculitis // Eur. Heart J.– 2019. Vol. 3, Issue 4.– P. 1–7. doi: 10.1093/ehjcr/ytz183.
5. Nozary Heshmati B., Ahmadi F., Azimi P et al. Hemodynamic factors affecting the suitability of the donated heart and kidney for transplantation // Int. J. Organ. Transplant. Med.– 2013.– Vol. 4 (4).– P. 150–154.
6. Tonsho M., Michel S., Ahmed Z. et al. Heart transplantation: challenges facing the field // Cold Spring Harbor perspectives in medicine.– 2014.– Vol. 4 (5).– P. a015636.  doi: 10.1101/cshperspect.a015636.
7. Yang H.Y., Lin C.Y., Tsai Y.T. et al. Experience of heart transplantation from hemodynamically unstable brain-dead donors with extracorporeal support // Clin. Transplant.– 2012.– Vol. 26 (5).– P. 792–796. doi: 10.1111/j.1399-0012.2011.01585.x.
8. Zuckermann A., Schulz U., Deuse T. et al. Thymoglobulin induction in heart transplantation: patient selection and implications for maintenance immunosuppression // Transplant international: Official Journal of the European Society for Organ Transplantation.– 2015.– Vol. 28 (3).– P. 259–269.  doi: 10.1111/tri.12480. 

The first clinical experience of Marshall’s vein alcohol ablation in complex treatment of persistent atrial fibrillation

V.V. Boiko, S.V. Rybchynskyi, D.O. Lopin, A.S. Vnukova, D.Ye. Volkov

References 

1. Bai R., Di Biase L., Mohanty P. et al. Proven isolation of the pulmonary vein antrum with or without left atrial posterior wall isolation in patients with persistent atrial fibrillation // Heart Rhythm.– 2016.– Vol. 13 (1).– P. 132–140. doi: 10.1016/j.hrthm.2015.08.019.
2. Boersma L., Koźluk E., Maglia G. et al. Paroxysmal and persistent atrial fibrillation ablation outcomes with the pulmonary vein ablation catheter GOLD duty-cycled phased radiofrequency ablation catheter: quality of life and 12-month efficacy results from the GOLD Atrial Fibrillation Registry // EP Europace.– 2020.– Vol. 22 (6).– P. 888–896. doi: 10.1093/europace/euaa042.
3. Brugada J., Katritsis D., Arbelo E. et al. 2019 ESC Guidelines for the management of patients with supraventricular tachycardia The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC) // Eur. Heart J.– 2019.– Vol. 41 (5).– P. 655–720.  doi: 10.1093/eurheartj/ehz467.
4. Choi J., Park E., Kim H. et al. Ethanol Infusion in the Vein of Marshall in a Patient with Persistent Atrial Fibrillation // Korean Circulation J.– 2015.– Vol. 45 (5).– P. 424. doi: 10.4070/kcj.2015.45.5.424.
5. Hacking C. Vein of Marshall Radiology Reference Article Radiopaedia.org // Retrieved 25 August 2020. https://radiopaedia.org/articles/vein-of-marshall-1?lang=us.
6. Hindricks G., Potpara T., Dagres N. et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS) // Eur. Heart J.– 2020. doi: 10.1093/eurheartj/ehaa612.
7. Hsu L., Jaïs P., Keane D. et al. Atrial fibrillation originating from persistent left superior vena cava // Circulation, 2004.– Vol. 109 (7).– P. 828–832. doi: 10.1161/01.cir.0000116753.56467.bc.
8. Kamanu S., Tan A., Peter C. et al. Vein of Marshall activity during sustained atrial fibrillation // J. Cardiovasc. Electrophysiology.– 2006.– Vol. 17 (8).– P. 839–846. doi: 10.1111/j.1540-8167.2006.00516.x.
9. Kirchhof P., Benussi S., Kotecha D. et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS // Eur. Heart J.– 2016.– Vol. 37 (38).– P. 2893–2962. doi: 10.1093/eurheartj/ehw210.
10. Kirchhof P., Camm A., Goette A. et al. Early rhythm-control therapy in patients with atrial fibrillation // New Engl. J. Medicine.– 2020.– Vol. 383 (14).– P. 1305–1316. doi: 10.1056/nejmoa2019422.
11. Kuck K., Brugada J., Schlüter M. et al. The FIRE AND ICE Trial: What we know, what we can still learn, and what we need to address in the future // J. Amer. Heart Association.– 2018.– Vol. 7 (24). doi: 10.1161/jaha.118.010777.
12. Lin W., Tai C., Hsieh M. et al. Catheter ablation of paroxysmal atrial fibrillation initiated by non–pulmonary vein ectopy // Circulation.– 2003.– Vol. 107 (25).– P. 3176–3183. doi: 10.1161/01.cir.0000074206.52056.2d.
13. Margulescu A., Mont L. Persistent atrial fibrillation vs paroxysmal atrial fibrillation: differences in management // Expert Review Of Cardiovascular Therapy.– 2017.– Vol. 15 (8).– P. 601–618. doi: 10.1080/14779072.2017.1355237.
14. Nielsen J., Johannessen A., Raatikainen P. et al. Long-term efficacy of catheter ablation as first-line therapy for paroxysmal atrial fibrillation: 5-year outcome in a randomised clinical trial // Retrieved.– 2020.– Vol. 27.
15. Noseworthy P., Gersh B., Kent D. et al. Atrial fibrillation ablation in practice: assessing CABANA generalizability // Eur. Heart J.– 2019.– Vol. 40 (16).– P. 1257–1264. doi: 10.1093/eurheartj/ehz085.
16. Philibert S., Amet D., De Chirac M., Laurent G. A case report of ethanol infusion in the vein of Marshall using the right jugular vein approach // Eur. Heart J. – Case Reports.– 2020. doi: 10.1093/ehjcr/ytaa260.
17. Valderrábano M. Vein of Marshall ethanol infusion for persistent atrial fibrillation – American College of Cardiology // Retrieved.– 2020.– 25 August. https://www.acc.org/latest-in-cardiology/clinical-trials/2020/03/26/22/46/venus.
18. Valderrábano M., Chen H., Sidhu J. et al. Retrograde ethanol infusion in the vein of Marshall // Circulation: Arrhythmia And Electrophysiology.– 2009.– Vol. 2 (1).– P. 50–56. doi: 10.1161/circep.108.818427.
19. Valderrábano M., Liu X., Sasaridis C. et al. Ethanol infusion in the vein of Marshall: Adjunctive effects during ablation of atrial fibrillation // Heart Rhythm.– 2009.– Vol. 6 (11).– P. 1552–1558. doi: 10.1016/j.hrthm.2009.07.036.
20. Valderrábano M., Peterson L., Bunge R. et al. Vein of Marshall ethanol infusion for persistent atrial fibrillation: VENUS and MARS clinical trial design // Amer. Heart J.– 2019.– Vol. 215.– P. 52–61. doi: 10.1016/j.ahj.2019.04.022.
21. Verma A., Sanders P., Macle L. et al. Substrate and Trigger Ablation for Reduction of Atrial Fibrillation Trial – Part II (STAR AF II): design and rationale // Amer. Heart J.– 2012.– Vol. 164 (1).– P. 1–6.e6. doi: 10.1016/j.ahj.2012.04.002. 

Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy

V.О. Yarosh, V.V. Babenko, O.E. Svyrydiuk, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

References  

1. Albers G.W., Marks M.P., Kemp S. et al. DEFUSE 3 Investigators. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging // New Engl. J. Med.– 2018.– Vol. 378.– P. 708–718. doi: 10.1056/NEJMoa1713973.
2. Bejot Y., Ben Salem D., Osseby G.V. et al. Epidemiology of ischemic stroke from atrial fibrillation in Dijon, France, from 1985 to 2006 // Neurology.– 2009.– Vol. 72.– P. 346–353. doi: 10.1212/01.wnl.0000341280.31919.bd.
3. Diener H.C., Connolly S.J., Ezekowitz M.D. et al. Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial // Lancet Neurol.– 2010.– Vol. 9 (12).– P. 1157–1163. doi: 10.1016/S1474-4422(10)70274-X.
4. Easton J.D., Lopes R.D., Bahit M.C. et al. Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: A subgroup analysis of the ARISTOTLE trial // Lancet Neurol.– 2012.– Vol. 11.– P. 503–511. doi: 10.1016/S1474-4422(12)70092-3.
5. Emberson J., Lees K.R., Lyden P. et al.; Stroke Thrombolysis Trialists' Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials // Lancet.– 2014.– Vol. 384.– P. 1929–1935. doi: 10.1016/S0140-6736(14)60584-5.
6. Freedman B., Martinez C., Katholing A., Rietbrock S. Residual risk of stroke and death in anticoagulant‐treated patients with atrial fibrillation // JAMA Cardiol.– 2016.– Vol. 1.– P. 366–368. doi: 10.1001/jamacardio.2016.0393.
7. Gupta A.C., Schaefer P.W., Chaudhry Z.A. et al. Interobserver reliability of baseline noncontrast CT Alberta Stroke Program Early CT Score for intra-arterial stroke treatment selection // Am. J. Neuroradiol.– 2012.– Vol. 33 (6).– P. 1046–1049. doi: 10.3174/ajnr.A2942.
8. Hacke W., Kaste M., Bluhmki E. et al; ECASS Investigators. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke // New Engl. J. Med.– 2008.– Vol. 359.– P. 1317–1329. doi: 10.1056/NEJMoa0804656.
9. Hankey G.J., Patel M.R., Stevens S.R. et al. Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: A subgroup analysis of ROCKET AF // Lancet Neurol.– 2012.– Vol. 11.– P. 315–322. doi: 10.1016/S1474-4422(12)70042-X.
10. L’Allinec V., Sibon I., Mazighi M. et al. MT in anticoagulated patients: Direct oral anticoagulants versus vitamin K antagonists // Neurology.– 2020.– Vol. 94 (8).– P. e842–e850. doi: 10.1212/WNL.0000000000008873.
11. Mozaffarian D., Benjamin E.J., Go A.S. et al. Heart disease and stroke statistics —2015 update: a report from the American Heart Association // Circulation.– 2015.– Vol. 131.– P. e29–322. doi: 10.1161/CIR.0000000000000350.
12. Nogueira R.G., Jadhav A.P., Haussen D.C. et al.; DAWN Trial Investigators. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct // New Engl. J. Med.– 2018.– Vol. 378 (1).– P. 11–21. doi: 10.1056/NEJMoa1706442.
13. Powers W.J., Rabinstein A.A., Ackerson T. et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association // Stroke.– 2019.– Vol. 50.– P. e344–e418. doi: 10.1161/STR.0000000000000211. 
14. Rost N.S., Giugliano R.P., Ruff C.T. et al. Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48) // Stroke.– 2016.– Vol. 47.– P. 2075–2082.
15. Seiffge D.J., Werring D.J., Paciaroni M. et al. Timing of anticoagulation after recent schaemic stroke in patients with atrial fibrillation // Lancet Neurol.– 2019.– Vol. 18.– P. 117–126. doi: 10.1161/STROKEAHA.116.013540. 
16. The top 10 causes of death: factsheet. https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death.
17. Thomalla G., Simonsen C.Z., Boutitie F. et al; WAKE-UP Investigators. MRI-guided thrombolysis for stroke with unknown time of onset // New Engl. J. Med.– 2018.– Vol. 379.– P. 611–622. doi: 10.1056/NEJMoa1804355.
18. Vranckx P., Valgimigli M., Heidbuchel H. The Significance of Drug-Drug and Drug-Food Interactions of Oral Anticoagulation // Arrhythm. Electrophysiol. Rev.– 2018.– Vol. 7 (1).– P. 55–61. doi:10.15420/aer.2017.50.1.