Original Research

Adsorption properties of blood serum in ischemic heart disease with atherosclerosis of peripheral vessels

G.A. Ignatenko1, Yu.O. Sіniachenko2, O.V. Sіniachenko1

1 M. Gorky Donetsk National Medical University, Ukraine

2 Institute of Urgent and Recovery Surgery named after V.K. Gusak of NAMS of Ukraine, Donetsk, Ukraine

The aim of the work was the estimation of adsorption properties of blood serum by the methods of maximum bubble pressure, axisymmetric drop shape analysis and the oscillating droplet in ischemic heart disease. We registered a decrease of interfacial activity indicators for short-time existence of surface, viscoelastic modulus and relaxation time of blood serum. Changes in the adsorption properties of blood are related to sex and age of patients, the severity of the disease and hypertension, type of hyperlipidemia, the presence, prevalence and severity of vascular sclerosis (first of all vertebrates). Blood adsorption disorders are involved in pathogenesis of atherosclerosis, determining the integral degree of arteries narrowing, stenosis of the carotid, subclavian, vertebral, femoral and tibial vessels, as well as the state of endothelium-dependent and endothelium-independent vasodilation.

Key words: atherosclerosis, heart, vessels, blood, serum, adsorption, rheology

 

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